Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL921684 | 0.77 | NPC1 (0.51) | NOTUMSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL1304374 | 0.68 | NOTUM (1.00) | NOTUMCES1GAASMN1; SMN2NOX1 | |
| SCHEMBL29850056 | 0.68 | NOTUM (1.00) | NOTUMCES1GAASMN1; SMN2NOX1 | |
| SCHEMBL3289324 | 0.67 | MGLL (0.47) | SMN1; SMN2KMT2AMEN1MGLLPOLB | |
| SCHEMBL5126303 | 0.67 | SMN1; SMN2 (0.68) | NOTUMCES1GAASMN1; SMN2NOX1 | |
| SCHEMBL11097554 | 0.66 | MGLL (0.46) | GAAKMT2AMEN1MGLLPOLB | |
| SCHEMBL18600523 | 0.66 | ALDH1A1 (0.64) | GAASMN1; SMN2KMT2AUSP2MAPT | |
| SCHEMBL27082534 | 0.66 | HSD17B10 (0.41) | NOTUMCES1GAASMN1; SMN2NOX1 | |
| SCHEMBL27423700 | 0.65 | NOTUM (0.48) | NOTUMCES1GAASMN1; SMN2NOX1 | |
| SCHEMBL12478981 | 0.65 | GFER (0.45) | GAASMN1; SMN2KMT2AMEN1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281361-A | Peroxide bleach, cationic nitrile precursor to activate bleach | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1994-01-25 | — | — | US | disclosed |