Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6318584 | 0.97 | GAA (0.59) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| Hydrochloric Acid SCHEMBL2429 | 0.97 | GAA (0.59) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL8620191 | 0.97 | GAA (0.59) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| Hydrochloric Acid SCHEMBL29749149 | 0.97 | GAA (0.59) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| Hydrochloric Acid SCHEMBL17164514 | 0.97 | GAA (0.59) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| Hydrochloric Acid SCHEMBL11128054 | 0.95 | GAA (0.56) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| Hydrochloric Acid SCHEMBL5379306 | 0.95 | GAA (0.56) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| Hydrochloric Acid SCHEMBL5015318 | 0.95 | GAA (0.56) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| Hydrochloric Acid SCHEMBL29184264 | 0.95 | GAA (0.56) | GAAALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL1705904 | 0.95 | GAA (0.62) | GAAALDH1A1SMN1; SMN2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114479037-B | Biodegradable polyester elastomer material and preparation method thereof | 东华大学 | 2022-11-25 | — | — | CN | claimed |
| CN-114479037-A | Biodegradable polyester elastomer material and preparation method thereof | 东华大学 | 2022-05-13 | — | — | CN | claimed |
| CN-111892703-B | Biodegradable thermoplastic polyester elastic material and preparation method thereof | 东华大学 | 2021-07-20 | — | — | CN | claimed |
| CN-111892703-A | Biodegradable thermoplastic polyester elastic material and preparation method thereof | 东华大学 | 2020-11-06 | — | — | CN | claimed |
| CN-117384192-A | Preparation method of glutaryl bridged gemini organic guanidine chelate and application of glutaryl bridged gemini organic guanidine chelate in catalyzing and synthesizing PBS (poly (butylene succinate)) polyester | 扬州普立特科技发展有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-114479037-B | Biodegradable polyester elastomer material and preparation method thereof | 东华大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-113004503-B | Polyester film-forming aqueous dispersion, liquid mulching film and application thereof | 杭州沃福生物科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114479037-A | Biodegradable polyester elastomer material and preparation method thereof | 东华大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113698583-A | Method for directly synthesizing high molecular weight polylactic acid | 刘青 | 2021-11-26 | — | — | CN | disclosed |
| CN-107879933-B | Preparation method of thermosensitive material p-methylbenzyl alcohol oxalic acid diester | 寿光富康制药有限公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-111892703-B | Biodegradable thermoplastic polyester elastic material and preparation method thereof | 东华大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-113004503-A | Polyester film-forming aqueous dispersion, liquid mulching film and application thereof | 杭州沃福生物科技有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-1556128-A | Technological method of catalytic synthesizing medical biodegradable material with biomass organic guanidine compound | 南开大学 | 2004-12-22 | — | — | CN | disclosed |
| CN-1556129-A | Technology method of synthesizing medical biodegradable material foom di(2-methoxy ethoxy) aluminium sodium hydride | 南开大学 | 2004-12-22 | — | — | CN | disclosed |
| CN-1401633-A | Process for synthesizing medical biodegradable material by bionic organic guanidine salt catalyst | UNIV NANKAI (CN) | 2003-03-12 | — | — | CN | disclosed |
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |