Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29749149 | 1.00 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL6318584 | 1.00 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL17164514 | 1.00 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL5015318 | 0.97 | GAA (0.56) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL5379306 | 0.97 | GAA (0.56) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL9308912 | 0.97 | GAA (0.56) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL11128054 | 0.97 | GAA (0.56) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL29184264 | 0.97 | GAA (0.56) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1705904 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| P-Xylene SCHEMBL8660591 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2287 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126150-B | Preparation method of azilsartan medoxomil potassium salt impurity a | 仁合益康集团有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-118255829-A | Preparation method of 11 alpha-hydroxy canrenone | 湖南新合新生物医药有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118184718-A | Aspergillus fumigatus furan galactomannan-oligosaccharide derivative and preparation method and application thereof | 山东大学 | 2024-06-14 | — | — | CN | claimed |
| CN-118139869-A | Isopropyl-D-glucopyranoside derivative, preparation method and application thereof | 陈令仪 | 2024-06-04 | — | — | CN | claimed |
| CN-117700374-A | Preparation method of chiral high morpholine-3-formic acid | 吉尔多肽生物制药(大连市)有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117085117-B | Helicobacter pylori resistant composition of chamomile extract and preparation method thereof | 浙江花开星辰生物科技有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-117285672-A | Preparation method of molecular film dispersion auxiliary agent | 江苏卡欧化工股份有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117126150-A | Preparation method of azilsartan medoxomil potassium salt impurity a | 仁合益康集团有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-117085117-A | Helicobacter pylori resistant composition of chamomile extract and preparation method thereof | 浙江花开星辰生物科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-116925255-A | Glycan, preparation method and application thereof, and antitumor drug | 北京大学 | 2023-10-24 | — | — | CN | claimed |
| EP-1453809-A1 | PROCESS FOR THE PREPARATION OF 4-METHYL-7-AMINOQUINOLONES | Ciba SC Holding AG (CH) | 2004-09-08 | — | — | EP | claimed |
| WO-2003050089-A1 | PROCESS FOR THE PREPARATION OF 4-METHYL-7-AMINOQUINOLONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-06-19 | — | — | WO | claimed |
| US-20030065173-A1 | Pyridone-fused azabicyclic- or cytisine derivatives, their preparation and their use in addiction therapy | O'NEILL BRIAN T (US) | 2003-04-03 | — | — | US | claimed |
| US-20030013869-A1 | Esters of cyclic ADP ribose derivatives | BOARD REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2003-01-16 | — | — | US | claimed |
| EP-0475042-B1 | Thermosetting compound and its production method | KANEGAFUCHI CHEMICAL IND (JP) | 2002-02-06 | — | — | EP | claimed |
| US-5391697-A | Workability; heat resistance; mechanical properties | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-02-21 | — | — | US | claimed |
| EP-0413200-B1 | Substituted 1,2-naphthoquinone-(2)-diazide-4-sulfonic acids, process for their production and their use | HOECHST AG (DE) | 1994-10-05 | — | — | EP | claimed |
| EP-0475042-A2 | Thermosetting compound and its production method | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-03-18 | — | — | EP | claimed |
| US-5077395-A | Nitrosation, sulfonation, reduction, oxidation, diazotization, alkylation or acylation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | claimed |
| US-4260746-A | Chemical intermediates useful to prepare cephalosporins | BEECHAM GROUP LIMITED (GB) | 1981-04-07 | — | — | US | claimed |