Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL969171 | 0.81 | ALDH1A1 (0.34) | ALDH1A1EPHX1POLB | |
| SCHEMBL2527720 | 0.73 | — | — | |
| SCHEMBL8761091 | 0.71 | POLB (0.38) | ALDH1A1EPHX1POLB | |
| SCHEMBL107453 | 0.70 | MMP1 (0.41) | ALDH1A1KDM4CEPHX1POLB | |
| SCHEMBL4271558 | 0.69 | EPHX1 (0.39) | ALDH1A1EPHX1POLB | |
| SCHEMBL5792978 | 0.69 | — | — | |
| SCHEMBL965801 | 0.67 | — | — | |
| SCHEMBL21776065 | 0.67 | — | — | |
| SCHEMBL14899337 | 0.65 | — | — | |
| SCHEMBL1525799 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302711-A | Ester cleavage process for use with β-lactams | ELI LILLY AND COMPANY (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0557035-A2 | An ester cleavage process for use with beta-lactams | ELI LILLY AND COMPANY (US) | 1993-08-25 | — | — | EP | disclosed |