Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 7/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 7/20 | 0.45 |
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7294475 | 0.99 | KDM1A (0.51) | KDM1ADRD2SLC6A4DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL7292922 | 0.84 | CHRM2 (0.59) | — | |
| Hydrochloric Acid SCHEMBL7287910 | 0.80 | NPY2R (0.49) | — | |
| SCHEMBL11044734 | 0.76 | KCNA5 (0.63) | KDM1ADRD2DRD3HTR2A | |
| SCHEMBL7346182 | 0.76 | GRIN2B (0.56) | KDM1ADRD2SLC6A4DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL11041972 | 0.75 | KCNA5 (0.61) | KDM1ADRD2DRD3HTR2A | |
| SCHEMBL11065756 | 0.73 | KDM1A (0.55) | KDM1ADRD2SLC6A4DRD3HTR1A | |
| SCHEMBL19046481 | 0.73 | KDM1A (0.64) | KDM1ADRD2SLC6A4DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL7309309 | 0.72 | KDM1A (0.42) | KDM1ADRD2SLC6A4DRD3HTR1A | |
| SCHEMBL8920578 | 0.72 | PDE3B (0.49) | KDM1ADRD2SLC6A4HTR2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306719-A | Cardiotonic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| US-5071856-A | CARBOSTYRIL DERIVATIVES AND SALTS THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| US-4886809-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |