Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309252 | 0.94 | AGTR1 (0.54) | AGTR1 | |
| SCHEMBL9310409 | 0.94 | — | — | |
| SCHEMBL9308979 | 0.93 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL9678102 | 0.92 | — | — | |
| SCHEMBL9311285 | 0.92 | AGTR1 (0.57) | AGTR1 | |
| SCHEMBL9695286 | 0.91 | — | — | |
| SCHEMBL9309765 | 0.89 | — | — | |
| SCHEMBL9308648 | 0.89 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL9311207 | 0.88 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL9677384 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| WO-1992020673-A1 | ANTIHYPOTENSIVE BENZOFURAN DERIVATIVES WITH N-LINKED 1H-IMIDAZOLYLMETHYL-5-CARBOXAMIDE SUBSTITUENTS | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |
| EP-0514216-A1 | Antihypotensive benzofuran derivatives with N-linked 1H-imidazolyl-methyl-5-carboxamide substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |