⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311418 | 0.94 | AGTR1 (0.52) | — | |
| SCHEMBL9311285 | 0.93 | AGTR1 (0.57) | — | |
| SCHEMBL9310409 | 0.93 | — | — | |
| SCHEMBL9312065 | 0.93 | — | — | |
| SCHEMBL9678258 | 0.92 | — | — | |
| SCHEMBL9678069 | 0.89 | — | — | |
| SCHEMBL9678102 | 0.88 | — | — | |
| SCHEMBL9309099 | 0.88 | AGTR1 (0.50) | — | |
| SCHEMBL9309499 | 0.88 | — | — | |
| SCHEMBL9310583 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514216-A1 | Antihypotensive benzofuran derivatives with N-linked 1H-imidazolyl-methyl-5-carboxamide substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |