Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490724 | 0.90 | TBXA2R (0.46) | TBXA2RTBXAS1SLC6A3 | |
| SCHEMBL9308117 | 0.88 | TBXAS1 (0.52) | TBXA2RTBXAS1ALDH1A1 | |
| Seratrodast SCHEMBL98402 | 0.88 | TBXAS1 (0.52) | TBXA2RTBXAS1ALDH1A1 | |
| Seratrodast SCHEMBL98403 | 0.88 | TBXAS1 (0.52) | TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL2458688 | 0.87 | TBXA2R (0.59) | TBXA2RTBXAS1SLC6A3 | |
| SCHEMBL9308585 | 0.87 | TBXAS1 (0.50) | TBXA2RTBXAS1SLC6A3 | |
| SCHEMBL2453660 | 0.85 | PDE4B (0.44) | TBXA2RTBXAS1 | |
| SCHEMBL2460183 | 0.84 | PDE4B (0.45) | TBXA2RTBXAS1 | |
| SCHEMBL7832557 | 0.79 | TBXAS1 (0.51) | TBXA2RTBXAS1ALDH1A1POLB | |
| SCHEMBL2459057 | 0.79 | TBXAS1 (0.42) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |