Oxirane

Oxirane

SCHEMBL9309514

C1CO1.CCCC(O)CC1CO1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
DAGLA Q9Y4D2 1/20 0.31
THRB P10828 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL990913 0.94
SCHEMBL13589341 0.94
Oxirane SCHEMBL8570225 0.85 DAGLA (0.47) ALDH1A1DAGLA
SCHEMBL3243068 0.82 ALDH1A1 (0.43) ALDH1A1DAGLATHRBSMN1; SMN2
SCHEMBL3235400 0.82 ALDH1A1 (0.43) ALDH1A1DAGLATHRBSMN1; SMN2
SCHEMBL981080 0.80 ALDH1A1 (0.35) ALDH1A1
SCHEMBL3238484 0.80 ALDH1A1 (0.47) ALDH1A1DAGLASMN1; SMN2
SCHEMBL21081918 0.78 ALDH1A1 (0.50) ALDH1A1DAGLA
SCHEMBL28001429 0.78 ALDH1A1 (0.50) ALDH1A1DAGLA
SCHEMBL27891494 0.78 ALDH1A1 (0.50) ALDH1A1DAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443412-B1 Highly concentrated emulsifiable concentrates of neophanes and azaneophanes for use in protection of plants HOECHST SCHERING AGREVO GMBH (DE) 1994-11-30 EP claimed
US-5354739-A A mixture of anionic, nonionic emulsifiers and alkanol as insecticides, miticides HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-11 US claimed
EP-0443405-B1 Concentrated aqueous emulsions of neophanes and azaneophanes for use in protection of plants HOECHST SCHERING AGREVO GMBH (DE) 1994-08-31 EP claimed
US-5198431-A CONCENTRATED AQUEOUS EMULSIONS OF NEOPHANES AND AZANEOPHANES FOR USE IN PLANT PROTECTION HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-30 US claimed
US-5371105-A Agrochemically active substrance mixed with crystal growth inhibitor HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-06 US disclosed
US-5354739-A A mixture of anionic, nonionic emulsifiers and alkanol as insecticides, miticides HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
US-5227402-A Concentrated aqueous microemulsions HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed
US-5198431-A CONCENTRATED AQUEOUS EMULSIONS OF NEOPHANES AND AZANEOPHANES FOR USE IN PLANT PROTECTION HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-30 US disclosed
US-5198431-A CONCENTRATED AQUEOUS EMULSIONS OF NEOPHANES AND AZANEOPHANES FOR USE IN PLANT PROTECTION HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-30 US disclosed
US-4870103-A Concentrated aqueous microemulsions HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-26 US disclosed