Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311340 | 0.89 | PPARG (0.49) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL7308446 | 0.88 | PPARG (0.47) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL9309819 | 0.88 | PPARG (0.48) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL1894428 | 0.87 | PPARG (0.50) | PPARGAGTR1ACHE | |
| SCHEMBL9308652 | 0.85 | PPARG (0.43) | PPARGSMN1; SMN2LMNAHTTMAPK1 | |
| SCHEMBL9309290 | 0.81 | PPARG (0.46) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL9310919 | 0.81 | PPARG (0.47) | PPARGSMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL9309747 | 0.80 | PPARG (0.43) | PPARG | |
| SCHEMBL9311025 | 0.76 | PPARG (0.49) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL9307715 | 0.76 | PPARG (0.49) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |