Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311340 | 0.95 | PPARG (0.49) | PPARGAGTR1AGTR2ACHEESR2 | |
| SCHEMBL1894428 | 0.89 | PPARG (0.50) | PPARGAGTR1ACHE | |
| SCHEMBL9309532 | 0.88 | PPARG (0.47) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL9309735 | 0.87 | PPARG (0.48) | PPARGAGTR1AGTR2ACHEESR2 | |
| SCHEMBL9308516 | 0.85 | PPARG (0.44) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL9309290 | 0.83 | PPARG (0.46) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL9310919 | 0.83 | PPARG (0.47) | PPARGAGTR1ACHEESR2 | |
| SCHEMBL9311025 | 0.82 | PPARG (0.49) | PPARGAGTR1AGTR2ACHEESR2 | |
| SCHEMBL9846092 | 0.81 | PPARG (0.45) | PPARGAGTR1AGTR2ACHEESR2 | |
| SCHEMBL9308512 | 0.79 | PPARG (0.45) | PPARGAGTR1AGTR2ACHEESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |