Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309779 | 0.85 | GABRB3 (0.44) | KDM4ESMN1; SMN2 | |
| SCHEMBL10682964 | 0.80 | MAPK1 (0.42) | MAPK1RXRARXRBRXRGCDK4 | |
| SCHEMBL7961959 | 0.77 | KMT2A (0.49) | MAPK1RXRARXRBRXRGCDK4 | |
| SCHEMBL9309033 | 0.77 | MAPK1 (0.54) | MAPK1RXRARXRBRXRGCDK4 | |
| SCHEMBL9526672 | 0.74 | MAPK1 (0.42) | MAPK1RXRARXRBRXRGCDK4 | |
| SCHEMBL9309547 | 0.73 | MAPK1 (0.38) | MAPK1RXRARXRBRXRGCDK4 | |
| Methane SCHEMBL10739351 | 0.72 | MAPK1 (0.37) | MAPK1RXRARXRBRXRGCDK4 | |
| SCHEMBL10739344 | 0.71 | MAPK1 (0.39) | MAPK1RXRARXRBRXRGCDK4 | |
| SCHEMBL9311365 | 0.71 | ALDH1A1 (0.47) | KDM4EL3MBTL1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL11091434 | 0.71 | MAPK1 (0.48) | MAPK1RXRARXRBRXRGCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321002-A | Herbicidal derivatives of 2-(1-aryl-4-cyano-5-pyrazolylmethyleneiminooxy)alkanoic acids | FMC CORPORATION (US) | 1994-06-14 | — | — | US | disclosed |