Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | POLG | P54098 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470739 | 0.90 | LMNA (0.52) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL8541689 | 0.88 | LMNA (0.50) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL8797148 | 0.88 | LMNA (0.50) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL8541693 | 0.88 | LMNA (0.50) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL8797151 | 0.88 | LMNA (0.50) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL9471195 | 0.88 | LMNA (0.50) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL10421043 | 0.88 | LMNA (0.50) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL9311419 | 0.82 | LMNA (0.54) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL10468438 | 0.80 | LMNA (0.55) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL9471029 | 0.80 | LMNA (0.55) | PDE3ALMNACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |