Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.41 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309787 | 0.83 | AGTR1 (0.42) | AGTR1AGTR2GP6 | |
| SCHEMBL9309317 | 0.79 | AGTR1 (0.48) | AGTR1AGTR2GP6 | |
| SCHEMBL28517096 | 0.70 | AGTR1 (0.56) | AGTR1AGTR2GP6 | |
| SCHEMBL965839 | 0.69 | AGTR1 (0.67) | AGTR1AGTR2GP6PDE4APDE4B | |
| SCHEMBL28517015 | 0.69 | AGTR1 (0.54) | AGTR1AGTR2GP6 | |
| SCHEMBL4639444 | 0.67 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL9309634 | 0.67 | AGTR1 (0.52) | AGTR1AGTR2GP6 | |
| SCHEMBL28515127 | 0.67 | AGTR1 (0.52) | AGTR1AGTR2GP6 | |
| SCHEMBL9309309 | 0.67 | AGTR1 (0.49) | AGTR1AGTR2GP6TLR7 | |
| SCHEMBL9309628 | 0.67 | AGTR1 (0.56) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |