Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.54 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517096 | 0.88 | AGTR1 (0.56) | AGTR1AGTR2GP6 | |
| SCHEMBL29183328 | 0.86 | AGTR1 (0.50) | AGTR1AGTR2GP6 | |
| SCHEMBL965839 | 0.84 | AGTR1 (0.67) | AGTR1AGTR2GP6 | |
| SCHEMBL28517678 | 0.82 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL7270473 | 0.81 | KDM4E (0.51) | — | |
| SCHEMBL4544029 | 0.81 | AGTR1 (0.54) | AGTR1AGTR2GP6 | |
| SCHEMBL18003201 | 0.79 | AGTR1 (0.61) | AGTR1AGTR2GP6 | |
| SCHEMBL28515127 | 0.79 | AGTR1 (0.52) | AGTR1AGTR2GP6 | |
| SCHEMBL8638896 | 0.78 | AGTR1 (0.58) | AGTR1AGTR2GP6 | |
| SCHEMBL17943651 | 0.77 | AGTR1 (0.62) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285509-A | Preparation method and medical application of carbostyril bridged quinolone imidazoles and analogues thereof | 西南大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-112194631-B | Schiff base bridged sulfaimidazole compound and preparation method and application thereof | 哈尔滨工业大学（深圳） | 2022-08-02 | — | — | CN | disclosed |
| CN-112194631-A | Schiff base bridged sulfaimidazole compound and preparation method and application thereof | 哈尔滨工业大学（深圳） | 2021-01-08 | — | — | CN | disclosed |