Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833657 | 0.87 | HDAC1 (0.49) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9308117 | 0.86 | TBXAS1 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Seratrodast SCHEMBL98402 | 0.86 | TBXAS1 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Seratrodast SCHEMBL98403 | 0.86 | TBXAS1 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9309807 | 0.85 | HDAC1 (0.49) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9307576 | 0.85 | MEN1 (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9308585 | 0.85 | TBXAS1 (0.50) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL2459057 | 0.83 | TBXAS1 (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9310852 | 0.82 | PTPRC (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9019233 | 0.82 | PTPRC (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232089-B1 | QUINONE AMIDES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1991-03-13 | — | — | EP | claimed |
| EP-0232089-A2 | Quinone amides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-08-12 | — | — | EP | claimed |
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0232089-B1 | QUINONE AMIDES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232089-A2 | Quinone amides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-08-12 | — | — | EP | disclosed |