Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309809 | 0.85 | FAAH (0.45) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL7833657 | 0.80 | HDAC1 (0.49) | CYP3A4NR1I2HDAC3HDAC1HDAC2 | |
| SCHEMBL9310852 | 0.80 | PTPRC (0.43) | PPARAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9019233 | 0.80 | PTPRC (0.43) | PPARAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9309807 | 0.79 | HDAC1 (0.49) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7831153 | 0.78 | HDAC1 (0.44) | ALDH1A1HPGDHDAC3HDAC1HDAC2 | |
| SCHEMBL7829363 | 0.78 | HDAC3 (0.44) | ALDH1A1CYP3A4CYP2D6CYP2C19HDAC3 | |
| SCHEMBL7831731 | 0.77 | HDAC2 (0.46) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9308117 | 0.77 | TBXAS1 (0.52) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| Seratrodast SCHEMBL98403 | 0.77 | TBXAS1 (0.52) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0232089-B1 | QUINONE AMIDES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232089-A2 | Quinone amides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-08-12 | — | — | EP | disclosed |