Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308512 | 0.95 | PPARG (0.45) | PPARGACHEAGTR1AGTR2ALDH1A1 | |
| SCHEMBL9308565 | 0.89 | PPARG (0.45) | PPARGAGTR1 | |
| SCHEMBL9308652 | 0.86 | PPARG (0.43) | PPARGACHEAGTR1AGTR2ALDH1A1 | |
| SCHEMBL9309735 | 0.85 | PPARG (0.48) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9309819 | 0.85 | PPARG (0.48) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9308992 | 0.84 | CYP1A2 (0.45) | PPARGACHEALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9308911 | 0.83 | PPARG (0.41) | PPARGACHEAGTR1AGTR2ALDH1A1 | |
| SCHEMBL9309739 | 0.82 | PPARG (0.39) | PPARGACHEALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7312142 | 0.80 | PPARG (0.46) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9311025 | 0.79 | PPARG (0.49) | PPARGACHEAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |