Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308280 | 0.92 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL10394462 | 0.88 | ALDH1A1 (0.59) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL10395086 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL5438533 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL9310418 | 0.82 | ALDH1A1 (0.58) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL9309261 | 0.82 | HPRT1 (0.57) | ADORA3HPRT1PNP | |
| SCHEMBL9308659 | 0.82 | HPRT1 (0.57) | ADORA3HPRT1PNP | |
| SCHEMBL9309087 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL8537379 | 0.80 | ALDH1A1 (0.56) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL8338176 | 0.80 | ALDH1A1 (0.56) | ALDH1A1LMNAALBMAPK1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |