Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 7/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537379 | 0.89 | ALDH1A1 (0.56) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL8338176 | 0.89 | ALDH1A1 (0.56) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL9310418 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL9309972 | 0.82 | PNP (0.53) | ALDH1A1LMNAADORA3HPRT1 | |
| SCHEMBL9309760 | 0.82 | PNP (0.53) | ALDH1A1LMNAADORA3HPRT1 | |
| SCHEMBL9309777 | 0.82 | PNP (0.53) | ALDH1A1LMNAADORA3HPRT1 | |
| SCHEMBL9309828 | 0.81 | ALDH1A1 (0.59) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL9308280 | 0.81 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL11161954 | 0.81 | AHCY (0.63) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL9309643 | 0.80 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |