SCHEMBL930993

SCHEMBL930993

CCCCC=C[Si](OCCC)(OCCC)OCCC

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 4/20 0.35
LPAR2 Q9HBW0 3/20 0.35
LPAR1 Q92633 2/20 0.35
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
F7 P08709 1/20 0.31
F3 P13726 1/20 0.31
FAAH O00519 2/20 0.31
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17633935 1.00 LPAR3 (0.35) LPAR3LPAR2LPAR1TSHRALDH1A1
SCHEMBL930549 0.94 LPAR3 (0.33) LPAR3LPAR2LPAR1
SCHEMBL17633707 0.94 LPAR3 (0.39) LPAR3LPAR2LPAR1TSHRALDH1A1
SCHEMBL17633708 0.94 LPAR3 (0.39) LPAR3LPAR2LPAR1TSHRALDH1A1
SCHEMBL28513578 0.92 FAAH (0.42) LPAR3LPAR2LPAR1FAAHTRPV1
SCHEMBL28483996 0.92 FAAH (0.42) LPAR3LPAR2LPAR1FAAHTRPV1
SCHEMBL17633728 0.92 FAAH (0.42) LPAR3LPAR2LPAR1FAAHTRPV1
SCHEMBL28508445 0.92 FAAH (0.42) LPAR3LPAR2LPAR1FAAHTRPV1
SCHEMBL17633729 0.92 FAAH (0.42) LPAR3LPAR2LPAR1FAAHTRPV1
SCHEMBL7937399 0.91 LPAR3 (0.35) LPAR3LPAR2LPAR1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2272878-B1 Coupled polymers and manufacturing method thereof TSRC CORP (TW) 2013-12-18 EP claimed
US-8481649-B2 Coupled polymers and manufacturing method thereof TSRC CORPORATION (TW) 2013-07-09 US claimed
CN-102212196-B Coupled copolymer and method for producing the same TSRC CORP 2013-03-06 CN claimed
CN-102212196-A Coupled copolymer and method for producing the same TSRC CORP 2011-10-12 CN claimed
US-20110009588-A1 COUPLED POLYMERS AND MANUFACTURING METHOD THEREOF TSRC CORPORATION (TW) 2011-01-13 US claimed
EP-2272878-A1 Coupled polymers and manufacturing method thereof TSRC Corporation (TW) 2011-01-12 EP claimed
US-11028256-B2 Silica-containing rubber compositions containing specified coupling agents and related methods BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2021-06-08 US disclosed
US-20200123349-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2020-04-23 US disclosed
CN-106062044-B Polysiloxane copolymer, and antistatic agent and resin composition containing same 信越化学工业株式会社 2019-11-26 CN disclosed
US-20170247532-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2017-08-31 US disclosed
EP-3197950-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS Bridgestone Americas Tire Operations, LLC (US) 2017-08-02 EP disclosed
CN-106062044-A Polysiloxane copolymer, and antistatic agent and resin composition containing same 信越化学工业株式会社 2016-10-26 CN disclosed
WO-2016048935-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2016-03-31 WO disclosed
EP-2272878-B1 Coupled polymers and manufacturing method thereof TSRC CORP (TW) 2013-12-18 EP disclosed
US-8481649-B2 Coupled polymers and manufacturing method thereof TSRC CORPORATION (TW) 2013-07-09 US disclosed
CN-102212196-B Coupled copolymer and method for producing the same TSRC CORP 2013-03-06 CN disclosed
CN-102212196-A Coupled copolymer and method for producing the same TSRC CORP 2011-10-12 CN disclosed
US-20110009588-A1 COUPLED POLYMERS AND MANUFACTURING METHOD THEREOF TSRC CORPORATION (TW) 2011-01-13 US disclosed
EP-2272878-A1 Coupled polymers and manufacturing method thereof TSRC Corporation (TW) 2011-01-12 EP disclosed