Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.44 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.43 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.43 |
| ▸ | ATIC | P31939 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308275 | 0.90 | MEN1 (0.53) | MPLCTRCCTRB1ENPP2CYP1A2 | |
| SCHEMBL9310020 | 0.85 | CYP1A2 (0.51) | MPLCTRCCTRB1ENPP2CYP1A2 | |
| SCHEMBL8779905 | 0.84 | ENPP2 (0.57) | MPLCTRCCTRB1ENPP2CYP1A2 | |
| SCHEMBL13980954 | 0.81 | CYP1A2 (0.56) | MPLCTRCCTRB1ENPP2CYP1A2 | |
| SCHEMBL10617409 | 0.79 | ENPP2 (0.53) | MPLCTRCCTRB1ENPP2CYP1A2 | |
| SCHEMBL9310445 | 0.78 | MPL (0.48) | MPLCTRCCTRB1ENPP2CYP1A2 | |
| SCHEMBL10393486 | 0.78 | CTRB1 (0.52) | MPLCTRCCTRB1ENPP2CYP1A2 | |
| SCHEMBL16488626 | 0.76 | PHLPP2 (0.66) | ENPP2CYP1A2CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL7588620 | 0.76 | PHLPP2 (0.64) | ENPP2CYP1A2CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL16488621 | 0.75 | CYP1A2 (0.53) | MPLCTRCCTRB1ENPP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298607-A | Reactive dyes for cotton | CIBA-GEIGY CORPORATION (US) | 1994-03-29 | — | — | US | disclosed |
| US-4808706-A | WET- AND LIGHFAST; SOLUBLE | CIBA-GEIGY CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |