Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308537 | 0.92 | AGTR1 (0.32) | AGTR1AGTR2MAPT | |
| Hydrochloric Acid SCHEMBL9310047 | 0.92 | AGTR1 (0.33) | MAPK1AGTR1AGTR2 | |
| SCHEMBL9309541 | 0.91 | — | — | |
| SCHEMBL9312813 | 0.91 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9310894 | 0.90 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9309367 | 0.89 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8548762 | 0.87 | ABCB11 (0.30) | AGTR1AGTR2 | |
| SCHEMBL9309949 | 0.87 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL9311255 | 0.86 | MAPK1 (0.30) | MAPK1SMN1; SMN2 | |
| SCHEMBL9310369 | 0.85 | AGTR1 (0.40) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | claimed |
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |