SCHEMBL9310025

SCHEMBL9310025

CCn1c(C)cc(-c2nnn[nH]2)c1-c1ccc(Cn2c(S(=O)(=O)CC)nc3c(C)ccnc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.39
AGTR2 P50052 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8560571 0.86 AGTR1 (0.51) AGTR1AGTR2
SCHEMBL9043269 0.85 AGTR2 (0.55) AGTR1AGTR2
SCHEMBL9310592 0.85 AGTR1 (0.42) AGTR1AGTR2
SCHEMBL9310167 0.85 AGTR1 (0.40) AGTR1AGTR2
SCHEMBL9309979 0.80 AGTR2 (0.35) AGTR1AGTR2
SCHEMBL9041311 0.78 AGTR2 (0.55) AGTR1AGTR2
SCHEMBL9042132 0.78 AGTR2 (0.56) AGTR1AGTR2
SCHEMBL9039767 0.77 AGTR2 (0.54) AGTR1AGTR2
SCHEMBL8942974 0.76 AGTR2 (0.43) AGTR1AGTR2
SCHEMBL8829242 0.76 AGTR2 (0.55) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354759-A Angiotenin II antagonizing heterocyclic compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-10-11 US disclosed
EP-0553682-A1 Imidazo 4,5-b pyridine derivatives as Angiotensin II antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-08-04 EP disclosed