Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066590 | 0.83 | SRD5A2 (0.64) | GRIN1GRIN2BSRD5A2CYP3A4GPBAR1 | |
| SCHEMBL6577636 | 0.83 | GPBAR1 (0.59) | CYP3A4GPBAR1ARNR3C1SHBG | |
| SCHEMBL3842363 | 0.83 | GPBAR1 (0.59) | CYP3A4GPBAR1ARNR3C1SHBG | |
| SCHEMBL11516238 | 0.83 | GPBAR1 (0.59) | CYP3A4GPBAR1ARNR3C1SHBG | |
| SCHEMBL11648659 | 0.81 | GPBAR1 (0.35) | GRIN1GRIN2BSRD5A2CYP3A4GPBAR1 | |
| SCHEMBL890668 | 0.79 | AKR1B10 (0.63) | SRD5A2CYP3A4GPBAR1AKR1B10AKR1B1 | |
| SCHEMBL11150042 | 0.79 | SRD5A2 (0.59) | SRD5A2CYP3A4GPBAR1AKR1B10AKR1B1 | |
| SCHEMBL1235822 | 0.79 | AKR1B10 (0.63) | SRD5A2CYP3A4GPBAR1AKR1B10AKR1B1 | |
| SCHEMBL10884379 | 0.78 | SRD5A2 (0.48) | GRIN1GRIN2BSRD5A2CYP3A4GPBAR1 | |
| SCHEMBL17927681 | 0.77 | CYP17A1 (0.48) | SRD5A2CYP3A4GPBAR1ARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6072994-A | — | — | None | — | — | JP | disclosed |
| JP-H0672994-A | 22-OXACHOLECALCIFEROL DERIVATIVE AND ITS PRODUCTION | CHUGAI PHARMACEUT CO LTD | 1994-03-15 | — | — | JP | disclosed |