Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.59 |
| ▸ | SHBG | P04278 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | MGAM | O43451 | 1/20 | 0.59 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.56 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516238 | 1.00 | GPBAR1 (0.59) | GPBAR1SHBGCYP3A4SERPINA6HSD17B10 | |
| SCHEMBL3842363 | 1.00 | GPBAR1 (0.59) | GPBAR1SHBGCYP3A4SERPINA6HSD17B10 | |
| SCHEMBL11043325 | 0.86 | GPBAR1 (0.59) | GPBAR1SHBGCYP3A4SERPINA6HSD17B10 | |
| SCHEMBL11043329 | 0.86 | GPBAR1 (0.59) | GPBAR1SHBGCYP3A4SERPINA6HSD17B10 | |
| SCHEMBL6446959 | 0.85 | GPBAR1 (0.43) | GPBAR1SHBGCYP3A4SERPINA6HSD17B10 | |
| SCHEMBL6434159 | 0.85 | GPBAR1 (0.43) | GPBAR1SHBGCYP3A4SERPINA6HSD17B10 | |
| SCHEMBL497888 | 0.85 | GPBAR1 (0.43) | GPBAR1SHBGCYP3A4SERPINA6HSD17B10 | |
| SCHEMBL9310044 | 0.83 | GRIN1 (0.48) | GPBAR1SHBGCYP3A4SERPINA6HSD17B10 | |
| SCHEMBL11150042 | 0.82 | SRD5A2 (0.59) | GPBAR1CYP3A4LMNACYP1A2CYP2C9 | |
| SCHEMBL1235822 | 0.82 | AKR1B10 (0.63) | GPBAR1CYP3A4LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404344-A2 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | Anabonix, Inc. (US) | 2004-04-07 | — | — | EP | claimed |
| WO-2003002058-A2 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | ANABONIX, INC. (US) | 2003-01-09 | — | — | WO | claimed |
| US-11730682-B2 | Self-standing cosmetic sheet | L'OREAL (FR) | 2023-08-22 | — | — | US | disclosed |
| EP-1414390-A1 | NANOCAPSULES CONTAINING A STEROID FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003013445-A1 | NANOCAPSULES CONTAINING A STEROID FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11730682-B2 | Self-standing cosmetic sheet | CUTA, DSG1, SUCLG1 | GPBAR1 4596/4885SHBG 554/4885CYP3A4 3902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.