Butane

Butane

SCHEMBL9310262

C=Cc1ccccc1CCC.CCCC

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
MITF O75030 1/20 0.35
THRB P10828 2/20 0.34
THRA P10827 1/20 0.34
LIPG Q9Y5X9 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
HTR1A P08908 1/20 0.32
TSHR P16473 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78218 0.98 ALDH1A1 (0.41) ALDH1A1MITFTHRBTHRALIPG
Dimethylamine SCHEMBL8716369 0.92 ALDH1A1 (0.38) ALDH1A1MITFTHRBTHRALIPG
Diethylamine SCHEMBL8715474 0.90 ALDH1A1 (0.36) ALDH1A1MITFTHRBTHRALIPG
SCHEMBL29480441 0.86 CYP3A4 (0.44) ALDH1A1MITFTHRBTHRALIPG
SCHEMBL28869 0.86 CYP3A4 (0.44) ALDH1A1MITFTHRBTHRALIPG
SCHEMBL595200 0.84 ALDH1A1 (0.48) ALDH1A1MITFTHRBTSHR
SCHEMBL29377653 0.84 ALDH1A1 (0.48) ALDH1A1MITFTHRBTSHR
SCHEMBL31099593 0.84 LIPG (0.50) THRBTHRALIPGCYP3A4CYP2D6
SCHEMBL714033 0.84 LIPG (0.50) THRBTHRALIPGCYP3A4CYP2D6
Benzene SCHEMBL28275266 0.84 CYP3A4 (0.42) ALDH1A1THRBTHRALIPGCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5326489-A Sulfonated polymer NIPPON SHOKUBAI CO., LTD. (JP) 1994-07-05 US disclosed
EP-0523300-B1 Electrorheological fluids NIPPON CATALYTIC CHEM IND (JP) 1994-01-19 EP disclosed
EP-0523300-A1 Electrorheological fluids NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) 1993-01-20 EP disclosed