Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266572 | 0.81 | ESR2 (0.49) | ESR2HTR2CMEN1GAAKMT2A | |
| SCHEMBL628247 | 0.79 | TSHR (0.46) | ESR2TP53SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18246497 | 0.78 | ESR2 (1.00) | ESR2 | |
| SCHEMBL9308995 | 0.77 | ESR2 (0.58) | ESR2TP53SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25531939 | 0.76 | ESR2 (0.64) | ESR2MEN1KMT2A | |
| SCHEMBL257216 | 0.76 | ESR2 (0.69) | ESR2LMNAMEN1GAAKMT2A | |
| SCHEMBL5144848 | 0.75 | CNR2 (0.49) | ESR2TP53SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5146562 | 0.75 | SLC6A2 (0.46) | TP53SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL25531651 | 0.74 | ESR2 (0.66) | ESR2SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL6902989 | 0.74 | SLC6A2 (0.49) | TP53SLC6A2SLC6A4SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447828-B1 | 4-(4-Tert-Butylphenyl)cyclohexylamines and fungicides containing them | BASF AG (DE) | 1994-05-04 | — | — | EP | disclosed |
| US-5290806-A | 4-(4-tert-butylphenyl) cyclohexylamines, and fungicides containing same | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-01 | — | — | US | disclosed |
| EP-0447828-A1 | 4-(4-Tert-Butylphenyl)cyclohexylamines and fungicides containing them | BASF Aktiengesellschaft (DE) | 1991-09-25 | — | — | EP | disclosed |