Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11840477 | 0.91 | ESR2 (0.59) | ESR2KDM4EGAAMEN1KMT2A | |
| SCHEMBL3322034 | 0.88 | ESR2 (0.55) | ESR2KDM4EGAAMEN1KMT2A | |
| SCHEMBL15541691 | 0.88 | ESR2 (0.55) | ESR2KDM4EGAAMEN1KMT2A | |
| SCHEMBL15541693 | 0.88 | ESR2 (0.55) | ESR2KDM4EGAAMEN1KMT2A | |
| SCHEMBL3322032 | 0.88 | ESR2 (0.55) | ESR2KDM4EGAAMEN1KMT2A | |
| SCHEMBL18246497 | 0.82 | ESR2 (1.00) | ESR2 | |
| SCHEMBL1570402 | 0.78 | MAPT (0.48) | ESR2GAAMEN1KMT2ASLC18A3 | |
| SCHEMBL1570533 | 0.77 | ESR2 (0.54) | ESR2KDM4EGAAMEN1KMT2A | |
| SCHEMBL25531651 | 0.77 | ESR2 (0.66) | ESR2KDM4EGAAMEN1KMT2A | |
| SCHEMBL1570534 | 0.77 | ESR2 (0.54) | ESR2KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574079-A | 2, 2-difluoro-N- (2-thioether cyclohexyl-1-alkene-1-base) acetamide and derivative and synthesis method thereof | 湖南工程学院 | 2021-03-30 | — | — | CN | claimed |
| CN-108840824-A | The preparation process of 4- phenyl cycloheptylamine | 遵义医学院附属医院 | 2018-11-20 | — | — | CN | disclosed |
| CN-108840824-A | The preparation process of 4- phenyl cycloheptylamine | 遵义医学院附属医院 | 2018-11-20 | — | — | CN | disclosed |
| US-10011559-B2 | Preparation of chiral amides and amines | SUNOVION PHARMACEUTICALS INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-10011559-B2 | Preparation of chiral amides and amines | SUNOVION PHARMACEUTICALS INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20180016224-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | SUNOVION PHARMACEUTICALS INC. | 2018-01-18 | — | — | US | disclosed |
| US-20180016224-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | SUNOVION PHARMACEUTICALS INC. | 2018-01-18 | — | — | US | disclosed |
| EP-2816024-B1 | Chiral amines | SUNOVION PHARMACEUTICALS INC (US) | 2017-08-02 | — | — | EP | disclosed |
| EP-3144303-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2017-03-22 | — | — | EP | disclosed |
| US-9556139-B2 | 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-6355634-B1 | OXIME DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-12 | — | — | US | disclosed |
| WO-2002018327-A2 | GUANIDINOBENZAMIDES AS MC4-R AGONISTS | CHIRON CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
| WO-2001044188-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |
| EP-0893434-A1 | Intermediates for the preparation of oximethers | Novartis AG (CH) | 1999-01-27 | — | — | EP | disclosed |
| EP-0703215-A1 | Aromatic compounds | CIBA-GEIGY AG (CH) | 1996-03-27 | — | — | EP | disclosed |
| EP-0447828-B1 | 4-(4-Tert-Butylphenyl)cyclohexylamines and fungicides containing them | BASF AG (DE) | 1994-05-04 | — | — | EP | disclosed |
| US-5290806-A | 4-(4-tert-butylphenyl) cyclohexylamines, and fungicides containing same | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-01 | — | — | US | disclosed |
| EP-0460575-A1 | Aromatic compounds | CIBA-GEIGY AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| EP-0447828-A1 | 4-(4-Tert-Butylphenyl)cyclohexylamines and fungicides containing them | BASF Aktiengesellschaft (DE) | 1991-09-25 | — | — | EP | disclosed |
| US-3960961-A | 4'-Fluoro-4-{[4-(phenyl)cyclohexyl]amino}butyrophenones and the salts thereof | THE UPJOHN COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10011559-B2 | Preparation of chiral amides and amines | PNMT, ALKBH5, ALKBH2 | ESR2 568/4885KDM4E 599/4885GAA 2043/4885 |
| US-20180016224-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | PNMT, ALKBH2, ALKBH5 | ESR2 626/4885KDM4E 466/4885GAA 1978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.