Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095339 | 0.79 | KMT2A (0.41) | KMT2ACYP4F2CYP4A11POLBL3MBTL1 | |
| SCHEMBL11092658 | 0.74 | LMNA (0.47) | KMT2APOLBALDH1A1 | |
| SCHEMBL9311254 | 0.72 | CYP4F2 (0.40) | CYP4F2CYP4A11POLBL3MBTL1ALDH1A1 | |
| SCHEMBL11088974 | 0.71 | CYP3A4 (0.42) | KMT2ACYP4F2CYP4A11POLBALDH1A1 | |
| SCHEMBL2515076 | 0.69 | NPC1 (0.42) | KMT2ACYP4F2CYP4A11L3MBTL1ALDH1A1 | |
| SCHEMBL9310488 | 0.69 | CYP4F2 (0.38) | KMT2ACYP4F2CYP4A11POLBL3MBTL1 | |
| SCHEMBL11086582 | 0.68 | KMT2A (0.54) | KMT2ACYP4F2CYP4A11POLBL3MBTL1 | |
| SCHEMBL9567286 | 0.67 | HDAC1 (0.40) | POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL3382084 | 0.67 | HPGD (0.63) | KMT2APOLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL11786130 | 0.67 | SMN1; SMN2 (0.64) | KMT2ACYP4F2CYP4A11POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486443-A | PROSTAGLANDIN-LIKE EFFECTS | BURROUGHS WELLCOME CO. (US) | 1984-12-04 | — | — | US | disclosed |