Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 19/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882712 | 0.85 | TBXAS1 (0.83) | TBXAS1TBXA2R | |
| Hydrochloric Acid SCHEMBL9733045 | 0.81 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL9195934 | 0.80 | TBXAS1 (0.69) | TBXAS1TBXA2R | |
| SCHEMBL8884111 | 0.76 | TBXAS1 (0.83) | TBXAS1TBXA2R | |
| SCHEMBL8883679 | 0.76 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL8884653 | 0.76 | TBXAS1 (0.83) | TBXAS1TBXA2R | |
| SCHEMBL9311379 | 0.75 | TBXAS1 (0.83) | TBXAS1TBXA2RALDH1A1 | |
| SCHEMBL9311375 | 0.75 | TBXAS1 (0.83) | TBXAS1TBXA2RALDH1A1 | |
| SCHEMBL8886110 | 0.75 | TBXAS1 (0.84) | TBXAS1TBXA2R | |
| SCHEMBL8882120 | 0.74 | TBXAS1 (0.65) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286736-A | Thromboxane antagonists and thromboxane synthetase inhibitors | DR. KARL THOMAE GMBH (DE) | 1994-02-15 | — | — | US | disclosed |
| EP-0487095-A1 | Pyridyl derivatives, medicines containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-05-27 | — | — | EP | disclosed |