Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 18/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310902 | 1.00 | TBXAS1 (0.53) | TBXAS1TBXA2RKDM4E | |
| SCHEMBL9311472 | 0.90 | TBXAS1 (0.48) | TBXAS1TBXA2RKDM4E | |
| SCHEMBL9311476 | 0.90 | TBXAS1 (0.48) | TBXAS1TBXA2RKDM4E | |
| SCHEMBL9312047 | 0.89 | TBXAS1 (0.47) | TBXAS1TBXA2RKDM4E | |
| SCHEMBL9311615 | 0.85 | TBXAS1 (0.56) | TBXAS1TBXA2RKDM4E | |
| SCHEMBL9311610 | 0.85 | TBXAS1 (0.56) | TBXAS1TBXA2RKDM4E | |
| SCHEMBL9313198 | 0.85 | TBXAS1 (0.52) | TBXAS1KDM4E | |
| SCHEMBL9312019 | 0.83 | TBXAS1 (0.57) | TBXAS1KDM4E | |
| SCHEMBL9312095 | 0.81 | TBXAS1 (0.52) | TBXAS1KDM4E | |
| SCHEMBL9311618 | 0.80 | TBXAS1 (0.57) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374641-A | Thromboxane synthetase inhibitors, prostaglandin H2 antagonist , anticoagulants and antiallergens | TERUMO KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0501876-A1 | N-(3-pyridylalkyl)sulfonamide derivative and pharmaceutical preparation containing thereof | TERUMO KABUSHIKI KAISHA (JP) | 1992-09-02 | — | — | EP | disclosed |