Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 16/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312956 | 0.89 | TBXAS1 (0.65) | TBXAS1KDM4EALDH1A1POLB | |
| SCHEMBL9313198 | 0.88 | TBXAS1 (0.52) | TBXAS1KDM4EALDH1A1POLB | |
| SCHEMBL9312095 | 0.87 | TBXAS1 (0.52) | TBXAS1KDM4EALDH1A1POLB | |
| SCHEMBL9312369 | 0.86 | AR (0.55) | TBXAS1KDM4E | |
| SCHEMBL9311618 | 0.85 | TBXAS1 (0.57) | TBXAS1 | |
| SCHEMBL9311669 | 0.83 | TBXAS1 (0.48) | TBXAS1KDM4EALDH1A1POLB | |
| SCHEMBL9310892 | 0.83 | TBXAS1 (0.53) | TBXAS1KDM4E | |
| SCHEMBL9310902 | 0.83 | TBXAS1 (0.53) | TBXAS1KDM4E | |
| SCHEMBL9311472 | 0.80 | TBXAS1 (0.48) | TBXAS1KDM4EALDH1A1 | |
| SCHEMBL9311476 | 0.80 | TBXAS1 (0.48) | TBXAS1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374641-A | Thromboxane synthetase inhibitors, prostaglandin H2 antagonist , anticoagulants and antiallergens | TERUMO KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0501876-A1 | N-(3-pyridylalkyl)sulfonamide derivative and pharmaceutical preparation containing thereof | TERUMO KABUSHIKI KAISHA (JP) | 1992-09-02 | — | — | EP | disclosed |