Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595 | 0.91 | CA1 (0.54) | CA1CA2MAPTPLA2G2APLA2G4A | |
| SCHEMBL12724 | 0.90 | MAPK14 (0.53) | CA1CA2MAPTPLA2G2APLA2G4A | |
| SCHEMBL8665 | 0.88 | CA1 (0.59) | CA1CA2MAPTPLA2G2APLA2G4A | |
| SCHEMBL8472 | 0.85 | GABRP (0.50) | CA1CA2MAPTPLA2G2APLA2G4A | |
| SCHEMBL15527966 | 0.85 | CA1 (0.56) | CA1CA2MAPTPLA2G2APLA2G4A | |
| SCHEMBL8612 | 0.85 | CA1 (0.56) | CA1CA2MAPTPLA2G2APLA2G4A | |
| SCHEMBL8648 | 0.85 | TNKS (0.50) | CA1CA2MAPTADORA3KMT2A | |
| SCHEMBL8102 | 0.85 | MAPK14 (0.42) | CA1CA2MAPTPLA2G2APLA2G4A | |
| SCHEMBL15528187 | 0.82 | CA1 (0.54) | CA1CA2MAPTPLA2G2APLA2G4A | |
| SCHEMBL9012 | 0.82 | MAPK14 (0.51) | CA1CA2MAPTMAPK14PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496567-A2 | NOVEL BENZOPYRAN KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2012-09-12 | — | — | EP | claimed |
| WO-2011055215-A2 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-05-12 | — | — | WO | claimed |
| CN-100436439-C | Dimeric isoflavones | NOVOGEN RES PTY LTD (AU) | 2008-11-26 | — | — | CN | disclosed |
| CN-1505618-A | Dimeric isoflavones | ŵ�ָ��о��ɷ�����˾ | 2004-06-16 | — | — | CN | disclosed |