Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311 | 0.91 | CA1 (0.56) | CA1CA2MAPTPTPN1PLA2G2A | |
| SCHEMBL9012 | 0.91 | MAPK14 (0.51) | CA1CA2MAPTPTPN1PPARG | |
| SCHEMBL8310 | 0.86 | GABRP (0.48) | CA1CA2MAPTPTPN1PPARG | |
| SCHEMBL15528187 | 0.86 | CA1 (0.54) | CA1CA2MAPTPTPN1PLA2G2A | |
| SCHEMBL8665 | 0.85 | CA1 (0.59) | CA1CA2MAPTPTPN1PLA2G2A | |
| SCHEMBL4613473 | 0.84 | PPARG (0.60) | CA1CA2MAPTPTPN1PLA2G2A | |
| SCHEMBL15527966 | 0.82 | CA1 (0.56) | CA1CA2MAPTPTPN1PLA2G2A | |
| SCHEMBL8612 | 0.82 | CA1 (0.56) | CA1CA2MAPTPTPN1PLA2G2A | |
| SCHEMBL12724 | 0.82 | MAPK14 (0.53) | CA1CA2MAPTPTPN1PLA2G2A | |
| SCHEMBL13726173 | 0.81 | AR (0.44) | CA1CA2MAPTPTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496567-A2 | NOVEL BENZOPYRAN KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2012-09-12 | — | — | EP | claimed |
| WO-2011055215-A2 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-05-12 | — | — | WO | claimed |