Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136369 | 0.78 | KAT6A (0.42) | HPGDHTTCES2CES1 | |
| SCHEMBL30064 | 0.78 | ACHE (0.42) | HPGDHTTL3MBTL1HDAC3HDAC4 | |
| SCHEMBL7811506 | 0.76 | HPGD (0.46) | HPGDHTTL3MBTL1CES2CES1 | |
| SCHEMBL489533 | 0.76 | HPGD (0.55) | HPGDHTTL3MBTL1CES2CES1 | |
| SCHEMBL12327908 | 0.76 | HPGD (0.55) | HPGDHTTL3MBTL1CES2CES1 | |
| SCHEMBL5342753 | 0.75 | HPGD (0.53) | HPGDHTTL3MBTL1CES2CES1 | |
| SCHEMBL12569725 | 0.75 | HPGD (0.44) | HPGDHTTL3MBTL1CES2CES1 | |
| SCHEMBL18506338 | 0.75 | HPGD (0.44) | HPGDHTTL3MBTL1CES2CES1 | |
| SCHEMBL7811504 | 0.75 | HPGD (0.53) | HPGDHTTL3MBTL1CES2CES1 | |
| SCHEMBL2396879 | 0.75 | HPGD (0.53) | HPGDHTTL3MBTL1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023368-A1 | POGOSTONE DERIVATIVES AND METHODS OF USING THE SAME | Hamyard Associates LLC (US) | 2020-01-30 | — | — | WO | disclosed |
| CN-107216232-A | Preparation method of parylene F | 昆山彰盛奈米科技有限公司 | 2017-09-29 | — | — | CN | disclosed |
| WO-2015028034-A1 | COMBINATION OF 2,3,5,6-TETRAFLUORO-4-METHYLBENZYL (Z)-(1 R)-CIS-3-(2-CHLORO-3,3,3-TRIFLUORO-1 -PROPENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATE WITH AT LEAST ONE INSECTICIDE, ACARICIDE, NEMATICIDE AND/OR FUNGICIDE. | CHEMINOVA A/S (DK) | 2015-03-05 | — | — | WO | disclosed |
| US-5336670-A | 2,2-dimethyl-3-(but-1-en-3-ynyl)-cyclopropane carboxylates | ROUSSEL-UCLAF (FR) | 1994-08-09 | — | — | US | disclosed |
| EP-0551035-A1 | 3-(but-1-en-3-ynyl)-2,2-dimethylcyclopropanecarboxylic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-07-14 | — | — | EP | disclosed |
| US-4879302-A | Certain oximino-cyclopropane carboxylates having insecticidal activity | ROUSSEL VCLAF (FR) | 1989-11-07 | — | — | US | disclosed |
| US-4551546-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-05 | — | — | US | disclosed |
| US-4429153-A | INSECTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-01-31 | — | — | US | disclosed |
| US-4405640-A | Substituted fluorobenzyl cyclopropane carboxylates useful as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-09-20 | — | — | US | disclosed |
| EP-0031199-A1 | Substituted benzyl esters of cyclopropane carboxylic acids and their preparation, compositions containing them and methods of combating insect pests therewith, and substituted benzyl alcohols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-01 | — | — | EP | disclosed |