Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16079417 | 1.00 | PAX8 (0.32) | PAX8PTGS2MITF | |
| SCHEMBL16079421 | 1.00 | PAX8 (0.32) | PAX8PTGS2MITF | |
| SCHEMBL16079350 | 1.00 | PAX8 (0.32) | PAX8PTGS2MITF | |
| SCHEMBL16077508 | 0.82 | — | — | |
| SCHEMBL21563384 | 0.70 | CYP19A1 (0.40) | PAX8PTGS2 | |
| SCHEMBL12121169 | 0.70 | — | — | |
| SCHEMBL3947301 | 0.69 | — | — | |
| SCHEMBL2376391 | 0.69 | — | — | |
| SCHEMBL3944987 | 0.69 | — | — | |
| SCHEMBL16079420 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374653-A | Iridoid derivatives and the use thereof as a drug | TSUMURA & CO. (JP) | 1994-12-20 | — | — | US | disclosed |