SCHEMBL21563384

SCHEMBL21563384

C=C1C(=O)OC2C1CCC(C)C1CCC(C)C12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 3/20 0.40
▸ PKM P14618 5/20 0.38
▸ NLRP3 Q96P20 2/20 0.38
▸ ALDH1A1 P00352 4/20 0.36
▸ LMNA P02545 3/20 0.36
▸ TP53 P04637 3/20 0.36
▸ CYP3A4 P08684 3/20 0.36
▸ NFKB1 P19838 2/20 0.36
▸ CYP1A2 P05177 2/20 0.36
▸ STAT6 P42226 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ PTGS2 P35354 2/20 0.36
▸ CASP1 P29466 1/20 0.36
▸ NFKB2 Q00653 1/20 0.36
▸ RELA Q04206 1/20 0.36
▸ CYP2D6 P10635 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ THPO P40225 1/20 0.36
▸ HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21527011 0.74 PKM (0.48) PKMNLRP3ALDH1A1LMNATP53
SCHEMBL21563387 0.71 MAPT (0.45) PKMNLRP3ALDH1A1CYP3A4MAPT
SCHEMBL16079350 0.70 PAX8 (0.32) PTGS2PAX8
SCHEMBL16079421 0.70 PAX8 (0.32) PTGS2PAX8
SCHEMBL9311266 0.70 PAX8 (0.32) PTGS2PAX8
SCHEMBL16079417 0.70 PAX8 (0.32) PTGS2PAX8
SCHEMBL29302856 0.69 — —
SCHEMBL17147743 0.66 CYP19A1 (0.56) CYP19A1PKMNLRP3ALDH1A1LMNA
SCHEMBL24453722 0.65 CYP19A1 (0.61) CYP19A1PKMNLRP3ALDH1A1LMNA
SCHEMBL22305507 0.64 PKM (0.41) CYP19A1PKMNLRP3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224882-A1 LIGHT SOURCE SEOUL VIOSYS CO LTD (KR) 2024-07-11 — — US disclosed
US-20240224882-A1 LIGHT SOURCE SEOUL VIOSYS CO LTD (KR) 2024-07-11 — — US disclosed
US-11778953-B2 Light source for plant cultivation SEOUL VIOSYS CO., LTD. (KR) 2023-10-10 — — US disclosed
US-11778953-B2 Light source for plant cultivation SEOUL VIOSYS CO., LTD. (KR) 2023-10-10 — — US disclosed
US-20220192103-A1 LIGHT SOURCE FOR PLANT CULTIVATION SEOUL VIOSYS CO., LTD. (KR) 2022-06-23 — — US disclosed
US-20210332062-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2021-10-28 — — US disclosed
US-11021488-B2 Hetero-substituted cyclic lactone analogues and uses thereof BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2021-06-01 — — US disclosed
US-20200060099-A1 LIGHT SOURCE FOR PLANT CULTIVATION SEOUL VIOSYS CO., LTD. (KR) 2020-02-27 — — US disclosed
US-20190345167-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2019-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345167-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF MCL1, BCL9L, DLD CYP19A1 2388/4885PKM 4063/4885NLRP3 4339/4885
US-11021488-B2 Hetero-substituted cyclic lactone analogues and uses thereof MCL1, BCL9L, DLD CYP19A1 2388/4885PKM 4063/4885NLRP3 4339/4885
US-20210332062-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF MCL1, BCL9L, DLD CYP19A1 2388/4885PKM 4063/4885NLRP3 4339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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