Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310918 | 0.94 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL9313041 | 0.91 | TSHR (0.65) | TSHRSMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL9311525 | 0.84 | TSHR (0.57) | TSHRSMN1; SMN2ALDH1A1POLBGAA | |
| SCHEMBL9311010 | 0.82 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1POLBGAA | |
| SCHEMBL9311342 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9765259 | 0.80 | GAA (0.53) | TSHRSMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL9311671 | 0.79 | TBXAS1 (0.50) | SMN1; SMN2 | |
| SCHEMBL9311656 | 0.78 | TSHR (0.53) | TSHRSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL9312306 | 0.78 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1POLBGAA | |
| SCHEMBL9312705 | 0.78 | TBXAS1 (0.44) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374641-A | Thromboxane synthetase inhibitors, prostaglandin H2 antagonist , anticoagulants and antiallergens | TERUMO KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0501876-A1 | N-(3-pyridylalkyl)sulfonamide derivative and pharmaceutical preparation containing thereof | TERUMO KABUSHIKI KAISHA (JP) | 1992-09-02 | — | — | EP | disclosed |