Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311342 | 0.94 | SMN1; SMN2 (0.44) | POLBMEN1KMT2AADAMTS4PPARG | |
| SCHEMBL9311347 | 0.84 | ADAMTS4 (0.47) | POLBMEN1KMT2AADAMTS4PPARG | |
| SCHEMBL9310918 | 0.82 | TSHR (0.61) | POLBMEN1KMT2AADAMTS4ALDH1A1 | |
| SCHEMBL9311344 | 0.78 | TSHR (0.59) | POLBMEN1KMT2AADAMTS4ALDH1A1 | |
| SCHEMBL11563720 | 0.75 | KMT2A (0.52) | TBXAS1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9311729 | 0.75 | S1PR1 (0.51) | TBXAS1TBXA2R | |
| SCHEMBL9311923 | 0.73 | TBXAS1 (0.53) | TBXAS1TBXA2R | |
| SCHEMBL9311671 | 0.73 | TBXAS1 (0.50) | TBXAS1SMN1; SMN2TBXA2R | |
| SCHEMBL11559524 | 0.73 | ALDH1A1 (0.55) | TBXAS1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9312134 | 0.73 | S1PR1 (0.49) | TBXAS1ALDH1A1MAPK1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374641-A | Thromboxane synthetase inhibitors, prostaglandin H2 antagonist , anticoagulants and antiallergens | TERUMO KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0501876-A1 | N-(3-pyridylalkyl)sulfonamide derivative and pharmaceutical preparation containing thereof | TERUMO KABUSHIKI KAISHA (JP) | 1992-09-02 | — | — | EP | disclosed |