SCHEMBL9311985

SCHEMBL9311985

O=C(CC(=O)Nc1ccccc1Cl)Nc1ccccc1Cl

nearest known ligand 0.75

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.75
MEN1 O00255 4/20 0.75
NPC1 O15118 2/20 0.64
RAB9A P51151 2/20 0.64
HPGD P15428 4/20 0.62
HTT P42858 1/20 0.62
CYP1A2 P05177 1/20 0.60
CYP2C19 P33261 1/20 0.60
POLB P06746 1/20 0.60
ALDH1A1 P00352 2/20 0.58
TSHR P16473 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
GAA P10253 1/20 0.58
KDM4E B2RXH2 1/20 0.58
P2RX7 Q99572 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29389982 0.90 KMT2A (0.68) KMT2AMEN1NPC1RAB9AHPGD
SCHEMBL17434797 0.90 KMT2A (0.68) KMT2AMEN1NPC1RAB9AHPGD
SCHEMBL9312170 0.89 KMT2A (0.62) KMT2AMEN1NPC1RAB9AHPGD
SCHEMBL9518769 0.88 KMT2A (0.66) KMT2AMEN1NPC1RAB9AHPGD
SCHEMBL300285 0.88 KMT2A (0.66) KMT2AMEN1NPC1RAB9AHPGD
SCHEMBL29554472 0.88 KMT2A (0.66) KMT2AMEN1NPC1RAB9AHPGD
SCHEMBL6072206 0.88 KMT2A (0.70) KMT2AMEN1NPC1RAB9AHPGD
SCHEMBL1272337 0.88 KMT2A (0.70) KMT2AMEN1NPC1RAB9AHPGD
SCHEMBL9313409 0.88 MEN1 (0.67) KMT2AMEN1NPC1RAB9AHPGD
SCHEMBL6075497 0.87 KMT2A (0.64) KMT2AMEN1NPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
WO-2013052585-A2 IRON(III) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-04-11 WO disclosed
US-5338642-A Diazo type recording material comprising two couplers wherein the novel coupler used is a bis-malonamide FUJI PHOTO FILM CO., LTD. (JP) 1994-08-16 US disclosed