Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311985 | 0.88 | KMT2A (0.75) | KMT2AMEN1KDM4ECYP1A2NPC1 | |
| SCHEMBL2169180 | 0.83 | MEN1 (0.68) | KMT2AMEN1KDM4ECYP1A2NPC1 | |
| SCHEMBL29389982 | 0.83 | KMT2A (0.68) | KMT2AMEN1CYP1A2NPC1RAB9A | |
| SCHEMBL17434797 | 0.83 | KMT2A (0.68) | KMT2AMEN1CYP1A2NPC1RAB9A | |
| SCHEMBL10138056 | 0.83 | KDM1A (0.69) | KMT2AMEN1KDM4ECYP1A2NPC1 | |
| SCHEMBL2175829 | 0.82 | CYP1A2 (0.75) | KMT2AMEN1KDM4ECYP1A2NPC1 | |
| SCHEMBL29537172 | 0.82 | CYP1A2 (0.75) | KMT2AMEN1KDM4ECYP1A2NPC1 | |
| SCHEMBL29554472 | 0.81 | KMT2A (0.66) | KMT2AMEN1CYP1A2NPC1RAB9A | |
| SCHEMBL300285 | 0.81 | KMT2A (0.66) | KMT2AMEN1CYP1A2NPC1RAB9A | |
| SCHEMBL6072206 | 0.81 | KMT2A (0.70) | KMT2AMEN1KDM4ECYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335046-B1 | Method for producing 2,4-dihydroxyquinoline derivatives | MITSUBISHI CHEM IND (JP) | 1993-12-01 | — | — | EP | disclosed |
| US-4904787-A | CYCLIZATION USING POLYPHOSPHORIC ACID; NONHYDROLIZING, ONE STEP | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0335046-A1 | Method for producing 2,4-dihydroxyquinoline derivatives | MITSUBISHI KASEI CORPORATION (JP) | 1989-10-04 | — | — | EP | disclosed |