Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15005698 | 0.83 | CA1 (0.37) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL11385338 | 0.81 | TSHR (0.37) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL14727820 | 0.81 | ALDH1A1 (0.44) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL1122754 | 0.79 | — | — | |
| SCHEMBL9099905 | 0.79 | — | — | |
| SCHEMBL820790 | 0.79 | — | — | |
| SCHEMBL12532807 | 0.78 | TSHR (0.39) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL4981942 | 0.77 | PAM (0.41) | TSHRALDH1A1 | |
| SCHEMBL27911733 | 0.77 | TSHR (0.36) | TSHRHSD17B10ALDH1A1 | |
| SCHEMBL9305101 | 0.77 | TSHR (0.42) | TSHRMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371001-A | Transesterification in the presence of carboxy-esterases or carboxyamidases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| US-5254718-A | Using enzyme catalyst; simplified separation, purification | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| WO-1992015547-A1 | ESTERS OF UNSYMMETRICALLY 2-SUBSTITUTED GLYCOLIC ACID DIMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |