Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.56 |
| ▸ | ATAD2 | Q6PL18 | 5/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | BPTF | Q12830 | 2/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310589 | 0.91 | PRKCZ (0.53) | BRD4ATAD2PRKCZLMNAGAA | |
| SCHEMBL82566 | 0.90 | BRD4 (0.55) | BRD4ATAD2HTR2CLMNAGAA | |
| Hydrochloric Acid SCHEMBL70439 | 0.89 | HTR2C (0.54) | BRD4ATAD2HTR2CLMNAGAA | |
| SCHEMBL27322594 | 0.87 | BRD4 (0.56) | BRD4ATAD2HTR2CPRKCZPIM1 | |
| SCHEMBL27583230 | 0.77 | PRKCZ (0.52) | BRD4ATAD2PRKCZKDM1A | |
| SCHEMBL27849930 | 0.76 | GAA (0.62) | LMNAGAAALOX12RAPGEF4 | |
| SCHEMBL82901 | 0.76 | BRD4 (0.54) | BRD4ATAD2HTR2CGAAPIM1 | |
| SCHEMBL29862480 | 0.75 | HTR1A (0.52) | BRD4ATAD2PRKCZPIM1PIM2 | |
| Hydrochloric Acid SCHEMBL68445 | 0.75 | BRD4 (0.52) | BRD4ATAD2HTR2CGAAPIM1 | |
| SCHEMBL21460267 | 0.74 | PRKCZ (0.59) | BRD4ATAD2PRKCZPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292738-A | Anti-virally active pyridazinamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-03-08 | — | — | US | disclosed |
| US-5157035-A | Viricides | JANSSEN PHARMACEUTICA N. V. (BE) | 1992-10-20 | — | — | US | disclosed |
| US-5001125-A | Anti-virally active pyridazinamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-03-19 | — | — | US | disclosed |
| EP-0156433-B1 | ANTI-VIRALLY ACTIVE PYRIDAZINAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0156433-A2 | Anti-virally active pyridazinamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-10-02 | — | — | EP | disclosed |