Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383632 | 1.00 | HDAC4 (0.37) | HDAC4KDM1AMAOBNPC1RAB9A | |
| SCHEMBL8383638 | 1.00 | HDAC4 (0.37) | HDAC4KDM1AMAOBNPC1RAB9A | |
| SCHEMBL8034504 | 0.96 | HDAC4 (0.35) | HDAC4KDM1AMAOBNPC1RAB9A | |
| SCHEMBL8382655 | 0.85 | S1PR3 (0.36) | HDAC4MAOBNPC1RAB9AS1PR1 | |
| SCHEMBL8382673 | 0.85 | RAB9A (0.37) | HDAC4KDM1AMAOBNPC1RAB9A | |
| SCHEMBL9313858 | 0.85 | RAB9A (0.37) | HDAC4KDM1AMAOBNPC1RAB9A | |
| SCHEMBL9311828 | 0.85 | KDM1A (0.50) | KDM1AMAOBDEGS1DRD2 | |
| SCHEMBL8378151 | 0.85 | KDM1A (0.50) | KDM1AMAOBDEGS1DRD2 | |
| SCHEMBL8382651 | 0.85 | S1PR3 (0.36) | HDAC4MAOBNPC1RAB9AS1PR1 | |
| SCHEMBL9312023 | 0.85 | S1PR3 (0.36) | HDAC4MAOBNPC1RAB9AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |