Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383638 | 0.96 | HDAC4 (0.37) | HDAC4KDM1AMAOBNPC1RAB9A | |
| SCHEMBL8383632 | 0.96 | HDAC4 (0.37) | HDAC4KDM1AMAOBNPC1RAB9A | |
| SCHEMBL9312290 | 0.96 | HDAC4 (0.37) | HDAC4KDM1AMAOBNPC1RAB9A | |
| SCHEMBL8034489 | 0.85 | DRD2 (0.39) | NPC1RAB9A | |
| SCHEMBL8034655 | 0.84 | HDAC4 (0.36) | HDAC4KDM1AMAOBNPC1RAB9A | |
| SCHEMBL8034773 | 0.84 | ACACB (0.32) | HDAC4 | |
| SCHEMBL9179048 | 0.83 | DRD2 (0.41) | — | |
| SCHEMBL9179061 | 0.83 | DRD2 (0.41) | — | |
| SCHEMBL9617265 | 0.83 | DRD2 (0.41) | — | |
| SCHEMBL9179054 | 0.83 | DRD2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497176-B1 | Four rings compounds and liquid crystal mixtures containing them | MERCK PATENT GMBH (DE) | 2000-04-05 | — | — | EP | disclosed |
| US-5478497-A | For electro-optical purposes | HOFFMANN-LA ROCHE INC. (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0497176-A2 | Four rings compounds and liquid crystal mixtures containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |