Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.57 |
| ▸ | MMP2 | P08253 | 14/20 | 0.57 |
| ▸ | MMP9 | P14780 | 14/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312300 | 1.00 | MMP1 (0.57) | MMP1MMP2MMP9TRPV1MAOA | |
| SCHEMBL9312217 | 0.89 | MAPT (0.58) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL10478111 | 0.89 | MAPT (0.58) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL10588017 | 0.88 | MAPT (0.58) | MMP1MMP2MMP9TRPV1KDM4E | |
| SCHEMBL10588022 | 0.88 | MAPT (0.58) | MMP1MMP2MMP9TRPV1KDM4E | |
| SCHEMBL10588239 | 0.87 | MAOB (0.56) | TRPV1MAOBMAPT | |
| SCHEMBL10587855 | 0.87 | TRPV1 (0.48) | TRPV1KDM4EALDH1A1MAPT | |
| SCHEMBL10585350 | 0.87 | MAOB (0.54) | TRPV1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL10587854 | 0.87 | TRPV1 (0.48) | TRPV1KDM4EALDH1A1MAPT | |
| SCHEMBL9312463 | 0.83 | TRPV1 (0.56) | MMP1MMP2MMP9TRPV1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373019-A | Pharmaceutical lactam compositions for inhibition of erythrocyte and thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-13 | — | — | US | disclosed |
| US-4985448-A | Ureidoindoles, pharmaceutical compositions and methods for erythrocyte and thrombocyte aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0327986-A2 | Medicaments containing lactams, substituted lactams and process for their preparation | Roche Diagnostics GmbH (DE) | 1989-08-16 | — | — | EP | disclosed |