Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312296 | 0.87 | MMP1 (0.57) | MAOBTRPV1MAPT | |
| SCHEMBL9312300 | 0.87 | MMP1 (0.57) | MAOBTRPV1MAPT | |
| SCHEMBL10478111 | 0.85 | MAPT (0.58) | MAOBMEN1MAPTKMT2A | |
| SCHEMBL9312217 | 0.85 | MAPT (0.58) | MAOBMEN1MAPTKMT2A | |
| SCHEMBL9314245 | 0.85 | TRPV1 (0.60) | MAOBTRPV1CA12CA9CA1 | |
| SCHEMBL9314251 | 0.85 | TRPV1 (0.60) | MAOBTRPV1CA12CA9CA1 | |
| SCHEMBL10588017 | 0.84 | MAPT (0.58) | TRPV1CA12CA9CA1CA2 | |
| SCHEMBL10588022 | 0.84 | MAPT (0.58) | TRPV1CA12CA9CA1CA2 | |
| SCHEMBL9314316 | 0.83 | HSPA9 (0.56) | TRPV1CA12CA9CA1CA2 | |
| SCHEMBL10585350 | 0.83 | MAOB (0.54) | MAOBTRPV1CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327986-A2 | Medicaments containing lactams, substituted lactams and process for their preparation | Roche Diagnostics GmbH (DE) | 1989-08-16 | — | — | EP | disclosed |