Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312303 | 1.00 | KDM1A (0.45) | KDM1AMAOBDRD2DGAT1L3MBTL1 | |
| SCHEMBL9718525 | 1.00 | KDM1A (0.45) | KDM1AMAOBDRD2DGAT1L3MBTL1 | |
| SCHEMBL8383468 | 0.91 | KDM1A (0.47) | KDM1AMAOBDRD2DGAT1PROKR1 | |
| SCHEMBL9313228 | 0.91 | KDM1A (0.47) | KDM1AMAOBDRD2DGAT1PROKR1 | |
| SCHEMBL9311451 | 0.87 | RAB9A (0.38) | KDM1AMAOBDRD2L3MBTL1SLC6A3 | |
| SCHEMBL8383599 | 0.87 | RAB9A (0.38) | KDM1AMAOBDRD2L3MBTL1SLC6A3 | |
| SCHEMBL8383595 | 0.87 | RAB9A (0.38) | KDM1AMAOBDRD2L3MBTL1SLC6A3 | |
| SCHEMBL9311454 | 0.87 | RAB9A (0.38) | KDM1AMAOBDRD2L3MBTL1SLC6A3 | |
| SCHEMBL9313837 | 0.85 | KDM1A (0.39) | KDM1AMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8382002 | 0.85 | KDM1A (0.39) | KDM1AMAOBKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |