Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311454 | 1.00 | RAB9A (0.38) | RAB9ASMN1; SMN2NPC1HSD17B10DRD2 | |
| SCHEMBL8383599 | 1.00 | RAB9A (0.38) | RAB9ASMN1; SMN2NPC1HSD17B10DRD2 | |
| SCHEMBL8383595 | 1.00 | RAB9A (0.38) | RAB9ASMN1; SMN2NPC1HSD17B10DRD2 | |
| SCHEMBL9313858 | 0.90 | RAB9A (0.37) | RAB9ASMN1; SMN2NPC1HSD17B10DRD2 | |
| SCHEMBL8382673 | 0.90 | RAB9A (0.37) | RAB9ASMN1; SMN2NPC1HSD17B10DRD2 | |
| SCHEMBL9312299 | 0.87 | KDM1A (0.45) | SMN1; SMN2DRD2SLC6A3KDM4EPROKR1 | |
| SCHEMBL9718525 | 0.87 | KDM1A (0.45) | SMN1; SMN2DRD2SLC6A3KDM4EPROKR1 | |
| SCHEMBL9718529 | 0.87 | MAPK10 (0.33) | RAB9ASMN1; SMN2NPC1HSD17B10SLC6A3 | |
| SCHEMBL9312596 | 0.87 | MAPK10 (0.33) | RAB9ASMN1; SMN2NPC1HSD17B10SLC6A3 | |
| SCHEMBL9312602 | 0.87 | MAPK10 (0.33) | RAB9ASMN1; SMN2NPC1HSD17B10SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |